BDBM50312168 1-(2,4-dimethoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea::CHEMBL1075666

SMILES COc1cc(OC)c(cc1NC(=O)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1)C(F)(F)F

InChI Key InChIKey=YAYODJGNSKFEGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312168   

TargetEphrin type-B receptor 4(Human)
Cgi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50312168(1-(2,4-dimethoxy-5-(trifluoromethyl)phenyl)-3-(3-(...)
Affinity DataIC50: 518nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed