BDBM50312285 CHEMBL1081534::N-((2S,4R)-2-methyl-1-(3-(trifluoromethoxy)benzoyl)-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylacetamide

SMILES C[C@H]1C[C@@H](N(C(C)=O)c2ccccc2)c2ccccc2N1C(=O)c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=APNWRWKPGBJTMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312285   

TargetProstaglandin D2 receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50312285(N-((2S,4R)-2-methyl-1-(3-(trifluoromethoxy)benzoyl...)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5% BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50312285(N-((2S,4R)-2-methyl-1-(3-(trifluoromethoxy)benzoyl...)
Affinity DataIC50: 106nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 50% human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50312285(N-((2S,4R)-2-methyl-1-(3-(trifluoromethoxy)benzoyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5% BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed