BDBM50312743 3-(5-methoxy-6-(4-methoxybenzyloxy)pyridin-3-yloxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine::CHEMBL1087280

SMILES COc1ccc(COc2ncc(Oc3nc(cnc3N)-c3cnn(C)c3)cc2OC)cc1

InChI Key InChIKey=WJUXNUKCGGIWMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312743   

LigandPNGBDBM50312743(3-(5-methoxy-6-(4-methoxybenzyloxy)pyridin-3-yloxy...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human CSF1R autophosphorylation expressed in HEK293 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
LigandPNGBDBM50312743(3-(5-methoxy-6-(4-methoxybenzyloxy)pyridin-3-yloxy...)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed