BDBM50313003 3-(5-chloro-1-methyl-1H-indol-3-yl)-4-(3-methoxyphenyl)-1H-pyrrole-2,5-dione::CHEMBL1081617

SMILES COc1cccc(c1)C1=C(C(=O)NC1=O)c1cn(C)c2ccc(Cl)cc12

InChI Key InChIKey=AKGYFGPTGCPJOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313003   

TargetProtein kinase C alpha type(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313003(3-(5-chloro-1-methyl-1H-indol-3-yl)-4-(3-methoxyph...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313003(3-(5-chloro-1-methyl-1H-indol-3-yl)-4-(3-methoxyph...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed