BDBM50313005 3-(1,2-dimethyl-1H-indol-3-yl)-4-(3-methoxyphenyl)-1H-pyrrole-2,5-dione::CHEMBL1080933

SMILES COc1cccc(c1)C1=C(C(=O)NC1=O)c1c(C)n(C)c2ccccc12

InChI Key InChIKey=XRPAAPKYUKNKSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313005   

TargetGlycogen synthase kinase-3 beta(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313005(3-(1,2-dimethyl-1H-indol-3-yl)-4-(3-methoxyphenyl)...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed