BDBM50313122 3-(3-chlorophenylsulfonyl)-6-methoxy-1-(pyrrolidin-3-yl)-1H-indole::CHEMBL1086720

SMILES COc1ccc2c(cn(C3CCNC3)c2c1)S(=O)(=O)c1cccc(Cl)c1

InChI Key InChIKey=YJDWCWUZTZSLNC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313122   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313122(3-(3-chlorophenylsulfonyl)-6-methoxy-1-(pyrrolidin...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313122(3-(3-chlorophenylsulfonyl)-6-methoxy-1-(pyrrolidin...)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed