BDBM50313174 (R)-2-((S)-1-ethyl-4-(4-isopropylphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide::CHEMBL1080883

SMILES CCn1nc(C)c2[C@H](CCc3ccc(cc3)C(C)C)N(CCc12)[C@@H](C(=O)NC)c1ccccc1

InChI Key InChIKey=IGOJZIQKSMEGBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313174   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313174((R)-2-((S)-1-ethyl-4-(4-isopropylphenethyl)-3-meth...)
Affinity DataIC50: 161nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313174((R)-2-((S)-1-ethyl-4-(4-isopropylphenethyl)-3-meth...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human OX2 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed