BDBM50313292 (1S,4S)-2-(bicyclo[2.2.1]heptan-2-yl)-5-(4-tert-butylphenylsulfonyl)-2,5-diazabicyclo[2.2.1]heptane::CHEMBL1081453

SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1C[C@@H]2C[C@H]1CN2C1CC2CCC1C2

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50313292   

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313292((1S,4S)-2-(bicyclo[2.2.1]heptan-2-yl)-5-(4-tert-bu...)
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313292((1S,4S)-2-(bicyclo[2.2.1]heptan-2-yl)-5-(4-tert-bu...)
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313292((1S,4S)-2-(bicyclo[2.2.1]heptan-2-yl)-5-(4-tert-bu...)
Affinity DataIC50: 75nMAssay Description:Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313292((1S,4S)-2-(bicyclo[2.2.1]heptan-2-yl)-5-(4-tert-bu...)
Affinity DataIC50: 77nMAssay Description:Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed