BDBM50313341 6-(cyclohexyl(cyclopropylmethyl)amino)-N-(4-(methylsulfonyl)phenyl)pyrimidine-4-carboxamide::CHEMBL1087664::US9150519, 1-112

SMILES CS(=O)(=O)c1ccc(NC(=O)c2cc(ncn2)N(CC2CC2)C2CCCCC2)cc1

InChI Key InChIKey=NJMCYRLHRLJVGZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313341   

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313341(6-(cyclohexyl(cyclopropylmethyl)amino)-N-(4-(methy...)
Affinity DataEC50:  193nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50313341(6-(cyclohexyl(cyclopropylmethyl)amino)-N-(4-(methy...)
Affinity DataEC50:  193nMpH: 7.4 T: 2°CAssay Description:Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 ug protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2016
Entry Details
US Patent