BDBM50313496 (S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentanoic acid::CHEMBL1086172

SMILES CCCCCCCOc1ccc(CC[C@](C)(N)CC(O)=O)cc1

InChI Key InChIKey=VBYQVUKISPYLQE-UHFFFAOYSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50313496   

TargetSphingosine 1-phosphate receptor 5(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50313496((S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentan...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human S1P5 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50313496((S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentan...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50313496((S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentan...)
Affinity DataIC50: 2.20E+4nMAssay Description:Agonist activity at human S1P2 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50313496((S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentan...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50313496((S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentan...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human S1P4 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed