BDBM50313802 (1R,3S)-3-(2-acetamidopropan-2-yl)-N-((2S,3S)-3-hydroxy-4-(3-isopropylbenzylamino)-1-phenylbutan-2-yl)cyclohexanecarboxamide::CHEMBL1084154

SMILES CC(C)c1cccc(CNC[C@H](O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCC[C@@H](C2)C(C)(C)NC(C)=O)c1

InChI Key InChIKey=JKZUWZCUDKMAKA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313802   

TargetBeta-secretase 2(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50313802((1R,3S)-3-(2-acetamidopropan-2-yl)-N-((2S,3S)-3-hy...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50313802((1R,3S)-3-(2-acetamidopropan-2-yl)-N-((2S,3S)-3-hy...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50313802((1R,3S)-3-(2-acetamidopropan-2-yl)-N-((2S,3S)-3-hy...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed