BDBM50313861 (R)-5-(6-chloro-4-(1-cyclopropylethyl)-3-oxo-3,4-dihydropyrazin-2-ylamino)-6-methoxy-2-methylpyrimidine-4-carbonitrile::CHEMBL1090738

SMILES COc1nc(C)nc(C#N)c1Nc1nc(Cl)cn([C@H](C)C2CC2)c1=O

InChI Key InChIKey=UJRRAIHHCRZSND-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313861   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50313861((R)-5-(6-chloro-4-(1-cyclopropylethyl)-3-oxo-3,4-d...)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed