BDBM50314069 CHEMBL1091690::N-(3-(2-(2-(2-(4-hydroxypiperidin-1-yl)ethylamino)pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide

SMILES OC1CCN(CCNc2cc(ccn2)-c2cc3nccc(-c4cccc(NC(=O)c5cccc(c5)C(F)(F)F)c4)n3n2)CC1

InChI Key InChIKey=VTMCXPIYMFDLKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314069   

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314069(N-(3-(2-(2-(2-(4-hydroxypiperidin-1-yl)ethylamino)...)
Affinity DataIC50: 66nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed