BDBM50314319 (Z)-N,N-diethyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-ylureido)benzofuran-2(3H)-ylidene)methyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)piperidine-4-carboxamide::CHEMBL1091694

SMILES CCN(CC)C(=O)C1CCN(CC1)c1ccnc2n(C)cc(\C=C3/Oc4ccc(NC(=O)Nc5cccnc5)cc4C3=O)c12

InChI Key InChIKey=WARFAAVACUFFOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314319   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314319((Z)-N,N-diethyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin...)
Affinity DataIC50: 115nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314319((Z)-N,N-diethyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin...)
Affinity DataIC50: 308nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed