BDBM50314331 (Z)-1-methyl-3-(2-((1-methyl-4-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-5-yl)urea::CHEMBL1090434

SMILES CNC(=O)Nc1ccc2O\C(=C/c3cn(C)c4nccc(-c5ccccc5)c34)C(=O)c2c1

InChI Key InChIKey=PVSQHIZSVDWRED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314331   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314331((Z)-1-methyl-3-(2-((1-methyl-4-phenyl-1H-pyrrolo[2...)
Affinity DataIC50: 37nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314331((Z)-1-methyl-3-(2-((1-methyl-4-phenyl-1H-pyrrolo[2...)
Affinity DataIC50: 233nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed