BDBM50314340 (Z)-1-(2-((4-(4-(3-(dimethylamino)pyrrolidine-1-carbonyl)piperidin-1-yl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-5-yl)-3-(pyridin-3-yl)urea::CHEMBL1091701

SMILES CN(C)C1CCN(C1)C(=O)C1CCN(CC1)c1ccnc2n(C)cc(\C=C3/Oc4ccc(NC(=O)Nc5cccnc5)cc4C3=O)c12

InChI Key InChIKey=IFLLAMPXDVHCSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314340   

LigandPNGBDBM50314340((Z)-1-(2-((4-(4-(3-(dimethylamino)pyrrolidine-1-ca...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314340((Z)-1-(2-((4-(4-(3-(dimethylamino)pyrrolidine-1-ca...)
Affinity DataIC50: 11nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed