BDBM50314352 4-hydroxy-2-((1-methyl-4-(4-methylpiperazin-1-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1090383

SMILES CN1CCN(CC1)c1ccnc2n(C)cc(\C=C3/Oc4cccc(O)c4C3=O)c12

InChI Key InChIKey=XKPJYTLNNLDKQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314352   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314352(4-hydroxy-2-((1-methyl-4-(4-methylpiperazin-1-yl)-...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314352(4-hydroxy-2-((1-methyl-4-(4-methylpiperazin-1-yl)-...)
Affinity DataIC50: 173nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed