BDBM50314461 (2S)-2-(methylamino)-N-((1S)-2-((2S)-2-(4-(naphthalen-1-yl)-5-(prop-1-ynyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)propanamide::CHEMBL1092184

SMILES CN[C@@H](C)C(=O)N[C@@H](C1CCOCC1)C(=O)N1CCC[C@H]1c1nc(c(s1)C#CC)-c1cccc2ccccc12

InChI Key InChIKey=WOZSGFALNANZEC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314461   

TargetE3 ubiquitin-protein ligase XIAP(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50314461((2S)-2-(methylamino)-N-((1S)-2-((2S)-2-(4-(naphtha...)
Affinity DataKi:  3.80E+4nMAssay Description:Antagonist activity at XIAP BIR3 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 7(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50314461((2S)-2-(methylamino)-N-((1S)-2-((2S)-2-(4-(naphtha...)
Affinity DataKi:  1.60E+5nMAssay Description:Antagonist activity at ML-IAP MLXBIR3SG domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed