BDBM50314509 5-(4-cyano-2-methylphenyl)-N-ethyl-N-(6-methoxypyridin-3-yl)pyrazine-2-carboxamide::CHEMBL1094002

SMILES CCN(C(=O)c1cnc(cn1)-c1ccc(cc1C)C#N)c1ccc(OC)nc1

InChI Key InChIKey=ZKKNPTBHTDGIHV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314509   

TargetOxytocin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314509(5-(4-cyano-2-methylphenyl)-N-ethyl-N-(6-methoxypyr...)
Affinity DataKi:  393nMAssay Description:Antagonist activity at human cloned OT receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314509(5-(4-cyano-2-methylphenyl)-N-ethyl-N-(6-methoxypyr...)
Affinity DataKi:  7.20E+3nMAssay Description:Antagonist activity at human cloned vasopressin V1A receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314509(5-(4-cyano-2-methylphenyl)-N-ethyl-N-(6-methoxypyr...)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human cloned vasopressin V2 receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed