BDBM50314632 CHEMBL1089701::N-hydroxy-3-(2-(2-(2-methyl-1H-indol-3-yl)ethyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)acrylamide

SMILES Cc1[nH]c2ccccc2c1CCN1CCc2cc(\C=C\C(=O)NO)ccc2C1

InChI Key InChIKey=OCUGVNIZKXOPTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314632   

TargetHistone deacetylase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314632(N-hydroxy-3-(2-(2-(2-methyl-1H-indol-3-yl)ethyl)-1...)
Affinity DataIC50: 41nMAssay Description:Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50314632(N-hydroxy-3-(2-(2-(2-methyl-1H-indol-3-yl)ethyl)-1...)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed