BDBM50314797 (3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosphinyl]-2-chloropropanoic Acid::CHEMBL1076865

SMILES N[C@@H](CCP(O)(=O)CC(Cl)C(O)=O)C(O)=O

InChI Key InChIKey=FQUOPRSIELVFTB-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50314797   

TargetMetabotropic glutamate receptor 2(Human)
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314797((3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  4.90E+4nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level after 1 hr by fluorescence micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314797((3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314797((3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  8.30E+3nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314797((3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  8.10E+3nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314797((3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314797((3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Rat)
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314797((3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  8.90E+3nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed