BDBM50314883 CHEMBL1089546::N-(3-Methylbenzyl)-N-(1-phenylethylpiperidine-4-yl)propionamide

SMILES CCC(=O)N(Cc1cccc(C)c1)C1CCN(CCc2ccccc2)CC1

InChI Key InChIKey=MZSFZQSYRHNECT-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50314883   

TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314883(N-(3-Methylbenzyl)-N-(1-phenylethylpiperidine-4-yl...)
Affinity DataIC50: 647nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314883(N-(3-Methylbenzyl)-N-(1-phenylethylpiperidine-4-yl...)
Affinity DataIC50: 610nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314883(N-(3-Methylbenzyl)-N-(1-phenylethylpiperidine-4-yl...)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314883(N-(3-Methylbenzyl)-N-(1-phenylethylpiperidine-4-yl...)
Affinity DataKi:  1.85E+3nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50314883(N-(3-Methylbenzyl)-N-(1-phenylethylpiperidine-4-yl...)
Affinity DataKi:  6.82E+3nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed