BDBM50314895 5-(5-methoxy-4-oxospiro[chroman-2,4'-piperidine]-1'-ylcarbonyl)-7-methyl-1H-indole-2-carboxamide::CHEMBL1090862

SMILES COc1cccc2OC3(CCN(CC3)C(=O)c3cc(C)c4[nH]c(cc4c3)C(N)=O)CC(=O)c12

InChI Key InChIKey=GQTIMACHULFKBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314895   

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314895(5-(5-methoxy-4-oxospiro[chroman-2,4'-piperidine]-1...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314895(5-(5-methoxy-4-oxospiro[chroman-2,4'-piperidine]-1...)
Affinity DataIC50: 65nMAssay Description:Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed