BDBM50315317 8-chloro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)benzofuro[3,2-d]pyrimidine::CHEMBL1092332

SMILES CN1C[C@@H]2C[C@H]1CN2c1ncnc2c1oc1ccc(Cl)cc21

InChI Key InChIKey=ZOXUBQNZEHLDQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315317   

TargetHistamine H4 receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50315317(8-chloro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2....)
Affinity DataIC50: 111nMAssay Description:Displacement of [3H]histamine dihydrochloride from human histamine H4 receptor after 2.5 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50315317(8-chloro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2....)
Affinity DataIC50: 70nMAssay Description:Inverse agonist activity at human histamine H4 receptor assessed as inhibition of [35S]GTPgammaS binding after 15 mins by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed