BDBM50315418 (1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methylphenyl]-1-thio-D-glucitol::CHEMBL1092287

SMILES CCOc1ccc(Cc2cc(ccc2C)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=VHPWZRKILUBNOT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315418   

TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315418((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methylphe...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315418((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methylphe...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315418((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methylphe...)
Affinity DataIC50: 671nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315418((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methylphe...)
Affinity DataIC50: 671nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed