BDBM50315475 CHEMBL1091606::N-(4-chlorophenylsulfonyl)-3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindolin-7-yl)acrylamide

SMILES FC1(F)C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=NZCUOOWQAWCQOB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315475   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315475(N-(4-chlorophenylsulfonyl)-3-(1-(2,4-dichlorobenzy...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315475(N-(4-chlorophenylsulfonyl)-3-(1-(2,4-dichlorobenzy...)
Affinity DataIC50: 251nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed