BDBM50315501 CHEMBL1088846::N-(3-chlorophenylsulfonyl)-3-(1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)acrylamide

SMILES Clc1cccc(c1)S(=O)(=O)NC(=O)\C=C\c1cccc2CC(=O)N(Cc3ccc4ccccc4c3)c12

InChI Key InChIKey=VIFRNWNCPJALHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315501   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315501(N-(3-chlorophenylsulfonyl)-3-(1-(naphthalen-2-ylme...)
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315501(N-(3-chlorophenylsulfonyl)-3-(1-(naphthalen-2-ylme...)
Affinity DataIC50: 8.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed