BDBM50315729 3-{7-[(Dimethylamino)methyl]-4-morpholin-4-yl-5H-pyrrolo-[3,2-d]pyrimidin-2-yl}phenyl)methanol::CHEMBL1088789

SMILES CN(C)Cc1c[nH]c2c(nc(nc12)-c1cccc(CO)c1)N1CCOCC1

InChI Key InChIKey=VXQJPJHEAPEQTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315729   

LigandPNGBDBM50315729(3-{7-[(Dimethylamino)methyl]-4-morpholin-4-yl-5H-p...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315729(3-{7-[(Dimethylamino)methyl]-4-morpholin-4-yl-5H-p...)
Affinity DataIC50: 108nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed