BDBM50315744 1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}phenyl)-3-ethylurea::CHEMBL1091159

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ccn(CCN(C)C)c2n1

InChI Key InChIKey=JLYIHNZUVHORKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315744   

LigandPNGBDBM50315744(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50: 226nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315744(1-(4-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed