BDBM50315748 1-{4-[7-(2,2-Dimethoxyethyl)-4-morpholin-4-yl-7H-pyrrolo-[2,3-d]pyrimidin-2-yl]phenyl}-3-pyridin-4-ylurea::CHEMBL1090781

SMILES COC(Cn1ccc2c(nc(nc12)-c1ccc(NC(=O)Nc2ccncc2)cc1)N1CCOCC1)OC

InChI Key InChIKey=WTSKLBVBUJRZSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315748   

LigandPNGBDBM50315748(1-{4-[7-(2,2-Dimethoxyethyl)-4-morpholin-4-yl-7H-p...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315748(1-{4-[7-(2,2-Dimethoxyethyl)-4-morpholin-4-yl-7H-p...)
Affinity DataIC50: 1nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed