BDBM50315760 1-{4-[(4-Methylpiperazin-1-yl)carbonyl]phenyl}-3-{4-[4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]phenyl}urea::CHEMBL1092074
SMILES CN1CCN(CC1)C(=O)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ccn(CC(F)(F)F)c3n2)cc1
InChI Key InChIKey=UMANUGUGHDROEQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50315760
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
