BDBM50316296 2,5-Dimethyl-8-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride::CHEMBL1095274

SMILES CN1CCc2c(C1)c1cc(ccc1n2C)S(=O)(=O)c1ccccc1

InChI Key InChIKey=DINGNQHSPYGDJO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316296   

Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50316296(2,5-Dimethyl-8-(phenylsulfonyl)-2,3,4,5-tetrahydro...)
Affinity DataIC50: 78nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production by LANCE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50316296(2,5-Dimethyl-8-(phenylsulfonyl)-2,3,4,5-tetrahydro...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity to human recombinant 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed