BDBM50317074 CHEMBL1087194::ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][1,8]naphthyridine-3-carboxylate

SMILES CCOC(=O)c1cc2c(N)c3CCCCc3nc2nc1C

InChI Key InChIKey=XGQUEKANWWMGAJ-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50317074   

TargetAcetylcholinesterase(Human)
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50317074(ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][...)
Affinity DataKi:  24nMAssay Description:Inhibition of AChE (unknown orign) by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Laboratorio De Radicales Libres Y QuÍMica Computacional (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50317074(ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][...)
Affinity DataIC50: 60nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50317074(ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][...)
Affinity DataIC50: 60nMAssay Description:Displacement of propidium iodide from AChE in bovine erythrocytes after 15 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Laboratorio De Radicales Libres Y QuÍMica Computacional (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50317074(ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][...)
Affinity DataIC50: 60nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50317074(ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][...)
Affinity DataIC50: 780nMAssay Description:Inhibition of AChE in human erythrocytes by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50317074(ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][...)
Affinity DataIC50: 780nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50317074(ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50317074(ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Equus caballus BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed