BDBM50317190 6-Hydroxy-2-[5-(6-hydroxy-beta-carboline-2-ium-2-yl)pentyl]-beta-carboline-2-ium dibromide::CHEMBL1096868

SMILES Oc1ccc2[nH]c3c[n+](CCCCC[n+]4ccc5c(c4)[nH]c4ccc(O)cc54)ccc3c2c1

InChI Key InChIKey=QTLHQXUXMHHSTK-UHFFFAOYSA-P

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317190   

TargetCholinesterase(Horse)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317190(6-Hydroxy-2-[5-(6-hydroxy-beta-carboline-2-ium-2-y...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317190(6-Hydroxy-2-[5-(6-hydroxy-beta-carboline-2-ium-2-y...)
Affinity DataIC50: 4.26E+3nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Friedrich-Schiller-Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50317190(6-Hydroxy-2-[5-(6-hydroxy-beta-carboline-2-ium-2-y...)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed