BDBM50317587 6-(2,4-difluorophenyl)-1-(2-fluoro-5-(1,3,4-oxadiazol-2-yl)phenyl)-2H-quinolizin-2-one::CHEMBL1098554

SMILES Fc1ccc(c(F)c1)-c1cccc2c(-c3cc(ccc3F)-c3nnco3)c(=O)ccn12

InChI Key InChIKey=AUNLMMZYXXUJGF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317587   

TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317587(6-(2,4-difluorophenyl)-1-(2-fluoro-5-(1,3,4-oxadia...)
Affinity DataIC50: 14.7nMAssay Description:Inhibition of mouse p38alpha after 3 hrs by SPA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317587(6-(2,4-difluorophenyl)-1-(2-fluoro-5-(1,3,4-oxadia...)
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of labeled MK-499 from human ERG in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed