BDBM50317647 (3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl-3-((S)-7-hydroxy-6-oxooctyl)decahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone::CHEMBL1096981

SMILES C[C@H](O)C(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O

InChI Key InChIKey=KZMKLVLLHNILJL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50317647   

TargetHistone deacetylase 3(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50317647((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of full length HDAC3 expressed in HEK293 cells after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50317647((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataIC50: 68nMAssay Description:Inhibition of full length HDAC1 expressed in HEK293 cells after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50317647((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataIC50: 179nMAssay Description:Inhibition of full length HDAC2 expressed in HEK293 cells after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50317647((3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of full length HDAC6 expressed in HEK293 cells after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed