BDBM50317844 4'-fluoro-4-(2-methylbenzo[d]thiazol-5-yl)biphenyl-2-carbonitrile::CHEMBL1096810

SMILES Cc1nc2cc(ccc2s1)-c1ccc(-c2ccc(F)cc2)c(c1)C#N

InChI Key InChIKey=YOHDJOWVKFHDNN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317844   

TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50317844(4'-fluoro-4-(2-methylbenzo[d]thiazol-5-yl)biphenyl...)
Affinity DataKi:  4.68E+3nMAssay Description:Displacement of [3HMPEP from rat cloned mGluR5 expressed in HEK293T cells by by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50317844(4'-fluoro-4-(2-methylbenzo[d]thiazol-5-yl)biphenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincubated for 140 secs befor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed