BDBM50318460 CHEMBL1085104::S-2,2,2-trichloro-1-(4-chlorobenzamido)ethyl ethanethioate

SMILES CC(=O)SC(NC(=O)c1ccc(Cl)cc1)C(Cl)(Cl)Cl

InChI Key InChIKey=SSONTNYBPYRIPQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318460   

LigandPNGBDBM50318460(S-2,2,2-trichloro-1-(4-chlorobenzamido)ethyl ethan...)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human TRPA1 channel assessed as inhibition of allyl isothiocyanate-induced intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318460(S-2,2,2-trichloro-1-(4-chlorobenzamido)ethyl ethan...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at TRPA1 channel in rat DRG neurons assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed