BDBM50318622 2-Imidazol-1-ylmethylxanthen-9-one::CHEMBL1083354

SMILES O=c1c2ccccc2oc2ccc(Cn3ccnc3)cc12

InChI Key InChIKey=FWPREHSGJHCERR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318622   

TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50318622(2-Imidazol-1-ylmethylxanthen-9-one | CHEMBL1083354)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of aromatase from human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50318622(2-Imidazol-1-ylmethylxanthen-9-one | CHEMBL1083354)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate after 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50318622(2-Imidazol-1-ylmethylxanthen-9-one | CHEMBL1083354)
Affinity DataIC50: 463nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed