BDBM50318672 (1R,3S)-5'-Chloro-3-methyl-2,3,4,9-tetrahydrospiro[beta-carboline-1,3'-indol-2'(1'H)-one::CHEMBL1083769

SMILES C[C@H]1Cc2c([nH]c3ccccc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21

InChI Key InChIKey=QGMFKGFHTXZZHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318672   

TargetCytochrome P450 2C9(Human)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50318672((1R,3S)-5'-Chloro-3-methyl-2,3,4,9-tetrahydrospiro...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsome by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50318672((1R,3S)-5'-Chloro-3-methyl-2,3,4,9-tetrahydrospiro...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed