BDBM50318708 CHEMBL1084517::Methyl 5-Amino-2-methyl-6,7,8,9,10,11-hexahydrocycloocta-[b][1,8]naphthyridine-3-carboxylate

SMILES COC(=O)c1cc2c(N)c3CCCCCCc3nc2nc1C

InChI Key InChIKey=MJNRKJNEVQCSGU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318708   

TargetAcetylcholinesterase(Bovine)
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50318708(Methyl 5-Amino-2-methyl-6,7,8,9,10,11-hexahydrocyc...)
Affinity DataIC50: 250nMAssay Description:Displacement of propidium iodide from AChE in bovine erythrocytes after 15 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50318708(Methyl 5-Amino-2-methyl-6,7,8,9,10,11-hexahydrocyc...)
Affinity DataIC50: 250nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50318708(Methyl 5-Amino-2-methyl-6,7,8,9,10,11-hexahydrocyc...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of AChE in human erythrocytes by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50318708(Methyl 5-Amino-2-methyl-6,7,8,9,10,11-hexahydrocyc...)
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed