BDBM50318943 4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-yloxy)benzonitrile::CHEMBL1084770

SMILES CCc1cn(CCO)c(CC)c1Oc1ccc(cc1)C#N

InChI Key InChIKey=BZNHAHNOAXOEDO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50318943   

TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 131nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of estrogen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed