BDBM50318949 6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one::CHEMBL1083071

SMILES Cn1ncc-2c1CCc1c-2c2C(=O)NCc2c2c3cc(ccc3[nH]c12)C1CCCCO1

InChI Key InChIKey=XDDKJJLWQBEZES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318949   

LigandPNGBDBM50318949(6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tet...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurementsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50318949(6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tet...)
Affinity DataIC50: 715nMAssay Description:Inhibition of human recombinant TIE-2 by time resolved fluorescence measurementsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed