BDBM50318951 9-ethyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one::CHEMBL1082438

SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cnn(C)c4CCc3c12)C1CCCCO1

InChI Key InChIKey=BUCPADLKYCJDQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318951   

LigandPNGBDBM50318951(9-ethyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurementsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50318951(9-ethyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human recombinant TIE-2 by time resolved fluorescence measurementsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed