BDBM50318967 CHEMBL1083454::rac-9-cyclopentyl-5-methyl-12-(tetrahydro-2H-pyran-2-yl)-5,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one

SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4cc(ccc4n(C4CCCC4)c32)C2CCCCO2)n1

InChI Key InChIKey=AANHDPNKSQAGIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318967   

LigandPNGBDBM50318967(rac-9-cyclopentyl-5-methyl-12-(tetrahydro-2H-pyran...)
Affinity DataIC50: 50nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50318967(rac-9-cyclopentyl-5-methyl-12-(tetrahydro-2H-pyran...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant TIE-2 by time resolved fluorescence measurementsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50318967(rac-9-cyclopentyl-5-methyl-12-(tetrahydro-2H-pyran...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant VEGFR2 by time resolved fluorescence measurementsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed