BDBM50318980 1-(2-allylphenoxy)-3-(1-methylpiperidin-4-ylamino)propan-2-ol::CHEMBL1083669

SMILES CN1CCC(CC1)NCC(O)COc1ccccc1CC=C

InChI Key InChIKey=DBKJAXLCJUCMFZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318980   

TargetBeta-2 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50318980(1-(2-allylphenoxy)-3-(1-methylpiperidin-4-ylamino)...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]cyanopindolol from human adrenergic beta2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50318980(1-(2-allylphenoxy)-3-(1-methylpiperidin-4-ylamino)...)
Affinity DataKi:  260nMAssay Description:Antagonist activity at human adrenergic beta-1 receptor expressed in CHOK1 cells assessed as inhibition of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50318980(1-(2-allylphenoxy)-3-(1-methylpiperidin-4-ylamino)...)
Affinity DataKi:  6.23E+3nMAssay Description:Antagonist activity at human adrenergic beta3 receptor expressed in CHOK1 cells assessed as inhibition of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed