BDBM50319154 4-Ethylsulfonylamino-8-methoxy-3-methyl-1-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine::CHEMBL1085375

SMILES CCCc1nc(C)c2c(NS(=O)(=O)CC)nc3ccc(OC)nc3n12

InChI Key InChIKey=DKHVXRYXLGJJEQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319154   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Biotie Therapies

Curated by ChEMBL

LigandBDBM50319154(4-Ethylsulfonylamino-8-methoxy-3-methyl-1-propyl-i...)Copy SMILESCopy InChI

Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/20/2010
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