BDBM50319232 6-{3-[2-phenethyl-1-(2-pyrrolidin-1-yl-ethyl)-1H-benzimidazole-5-carbonyl]-ureido}-hexanoic acid hydroxyamide::CHEMBL1084357

SMILES ONC(=O)CCCCCNC(=O)NC(=O)c1ccc2n(CCN3CCCC3)c(CCc3ccccc3)nc2c1

InChI Key InChIKey=FLEMUVTXATYOIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319232   

TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50319232(6-{3-[2-phenethyl-1-(2-pyrrolidin-1-yl-ethyl)-1H-b...)
Affinity DataIC50: 34nMAssay Description:Inhibition of HDAC1 in human COLO205 cells assessed as induction of histone H3 acetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50319232(6-{3-[2-phenethyl-1-(2-pyrrolidin-1-yl-ethyl)-1H-b...)
Affinity DataIC50: 5.38E+3nMAssay Description:Inhibition of HDAC1 in human COLO205 cells assessed as induction of histone H3 acetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed