BDBM50319500 CHEMBL1084450::N-(3-(4-benzamido-1H-pyrrolo[3,2-c]pyridin-1-yl)phenyl)-4-morpholino-3-(trifluoromethyl)benzamide

SMILES FC(F)(F)c1cc(ccc1N1CCOCC1)C(=O)Nc1cccc(c1)-n1ccc2c(NC(=O)c3ccccc3)nccc12

InChI Key InChIKey=FDCXXPBBHPICRU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50319500   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50319500(N-(3-(4-benzamido-1H-pyrrolo[3,2-c]pyridin-1-yl)ph...)
Affinity DataIC50: 96nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50319500(N-(3-(4-benzamido-1H-pyrrolo[3,2-c]pyridin-1-yl)ph...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50319500(N-(3-(4-benzamido-1H-pyrrolo[3,2-c]pyridin-1-yl)ph...)
Affinity DataIC50: 96nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50319500(N-(3-(4-benzamido-1H-pyrrolo[3,2-c]pyridin-1-yl)ph...)
Affinity DataIC50: 30nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50319500(N-(3-(4-benzamido-1H-pyrrolo[3,2-c]pyridin-1-yl)ph...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed