BDBM50319661 (R)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropylthiazol-4(5H)-one::CHEMBL1085105::CHEMBL1085839

SMILES CC(C)c1sc(N[C@@H]2C[C@H]3CC[C@@H]2C3)nc1O

InChI Key InChIKey=KUEKSTOVOGPIFY-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319661   

LigandPNGBDBM50319661(CHEMBL1085105 | CHEMBL1085839 | (R)-2-((1R,2R,4S)-...)
Affinity DataKi:  227nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319661(CHEMBL1085105 | CHEMBL1085839 | (R)-2-((1R,2R,4S)-...)
Affinity DataKi:  770nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319661(CHEMBL1085105 | CHEMBL1085839 | (R)-2-((1R,2R,4S)-...)
Affinity DataIC50: 931nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in HEK293 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319661(CHEMBL1085105 | CHEMBL1085839 | (R)-2-((1R,2R,4S)-...)
Affinity DataIC50: 1.51E+3nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in HEK293 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed